Wednesday, 27 February 2013

Allergic rhinitis


Allergic rhinitis seems to be the buzz word now in Hong Kong, and in most urban cities in China nowadays. With the ever increasing Air Pollution index (API) being daily monitored, most Hong Kongers are not only aware of allergic rhinitis but are probably most likely sufferers of this condition.

Rhinitis is the medical term for inflammation of the nose (rhino-itis) and when the cause is an allergen that causes an allergic response, we call it allergic rhinitis. What is the related impact of this condition? Looking at this condition globally, it is estimated that 20% of everyone on Planet Earth is affected by rhinitis; that is to say one in every five persons. In the United States, an estimated 58 million Americans suffer from allergic rhinitis due to some allergens, whilst another 19 million have non-allergic rhinitis. This accounts for almost 30% of clinic attendances seen by the average Ear, Nose and Throat Specialist.

Most allergic rhinitis sufferers are usually allergic to things like house dust mite extracts (not house dust), pollen, cockroach extracts, molds and fungi. The fur or dander of pets like cats and dogs can also stimulate an allergy. So what happens when this occur?
       
Our nose is a very fine and sensitive organ. It regulates the temperature and humidity of the air entry in order to protect our lung, as well as to cleanse the entering air of particulate matter that would otherwise damage our lungs.

In the presence of house dust mite extract or molds, the blood flow to the nose will increase and cause the tissues in our nose (the turbinates) to swell.  This blocks air entry in to the nose; so we suffer from blocked nose. The nose starts to secrete copious amounts of mucus to irrigate away these allergens; we then suffer with a running nose, usually with a postnasal drip. And finally the chemical mediators released in an allergic reaction in the nose causes us to sneeze; this removes the allergens from our nose with a violent blow.
       
Allergic rhinitis, although considered as a disease, is best viewed as our body’s natural and protective response to contaminated air entering our body. There is no fever as there are no viruses or bacterial infection. It can occur everyday unlike e.g. viral infections that runs a course 2-3 times a year. And as the nasal passages get swollen, the sufferer often encounters other associated conditions like:
  •  Sinusitis and sinus headaches becomes more likely as the sinus openings are blocked
  • Mouth breathing to compensate for the blocked nose often ensues. This results in dry mouth, bad breath, recurrent sore throats and tonsillitis, recurrent mouth ulcers and poor sleep quality
  •  Recurrent tonsillitis will result in enlarged tonsils. This is a cause of snoring and obstructive sleep apnea, with a poorer sleep quality.
  •  A poorer sleep quality over time can affect one’s ability to function well cognitively with memory loss, irritability and frustration as well as maintaining a normal blood pressure for one’s age.
  •  Bronchial hyperactivity with dry cough and exacerbation of asthma is a common sequelae of poorly controlled allergic rhinitis. The simple reason for this is that the nose, mouth and lung airway share the same mucosal lining. So when the nose is no longer able to prevent soiling of the lung by the poor air e.g. because of mouth breathing, dry cough with asthmatic episodes increase.
  •  As the eyes have a similar lining that is equally reactive and similarly innervated by the nose, allergic rhinitis causes the eyes to stream tears, be itchy and cause blur vision and difficulty with wearing contact lenses comfortably.


So how can we treat allergic rhinitis? Whatever we do, we need to do regularly as most individuals are allergic to the ubiquitous house dust, which is everywhere. We need to remove the allergens. Simply avoiding would help but it is not always practical. Keeping our home and work environment dust free will help by wiping with a moist cloth, cleaning air-conditioning filters regularly, washing bed linen in water >63 degree Celsius to kill the house dust mites, avoid carpets if possible or at least keep them clean regularly.

The simplest way is to use a low pressure, high volume nasal saline douching system for the nose. These are available from the local chemists. They irrigate the nose, keeping the allergen load at a minimum and should be a part of one’s daily hygiene regime to maximize the benefit.

Whilst the above would work for the mild sufferers, often medication is required. The commonest prescribed medication is a topical nasal steroid, which are anti-inflammatory.

They are very effective in reducing inflammation of the nasal lining topically at the target site of the condition, improving the nasal airway and reducing the secretions and itchiness. Unlike the dreaded injected or orally taken steroids, topical nasal steroids have been shown to be very safe to use in children as young as 3 years. Antihistamines oral medications are also used and they are especially effective in reducing the sneezing and runny nose.

So what about surgery for allergic rhinitis? In patients whose main problem with their rhinitis is a blocked nose with sinus related headaches and mouth breathing; surgery helps to unblock the nose. Enlarged turbinates can be reduced, deviated septum can be realigned and sinuses can be re-ventilated as necessary. As surgery does not remove the nasal lining completely, there may be residual allergic symptoms of sneezing and runny nose. However with a more patent nose, saline douching and/or topical nasal steroids will be more effective in reaching their target, and to minimize inflammation of this lining.

Allergic rhinitis is a condition that can affect the quality of life of the sufferer. With the sinusitis, poor sleep, reduced cognition, recurrent throat infections, obstructive sleep apnea and asthma that can be associated with it, it adds to the “unseen” economic loss for employers and the Hong Kong community as a whole. Simple measures and medication do help, but just sometimes surgery is required to better control the condition.

Case study

A 39 year old executive presented with a blocked nose, dry mouth, snoring, with poor sleep and morning headaches. His turbinates were swollen and they blocked the nose. When the turbinates were decongested for a full nasal examination, a deviated bony septum was seen and an enlarged postnasal adenoid was seen. With the blocked nose and daily mouth breathing, the tonsils and pharynx were inflamed and enlarged. The tonsils added to the snoring, which when he reached the deeper stages of sleep, together with a relaxed tongue, caused an airway obstruction during sleep. Hence good deep sleep was not always possibly attained. In spite of medication, the condition did not improve, and surgery was offered.

Surgery, to straighten the nasal septum, reduce the inferior turbinates, remove the tonsils and trim the elongated uvula, was performed. The improvement in the airway was significant and resulted in a better sleep, minimal snoring and an overall improved quality of life and work. Regular nasal saline douching daily was still required to maintain good nasal hygiene.

More information: http://www.entific.com.hk/



The Chinese version of this article was published in Hong Kong Economic Journal  on February 14 & 28, 2013.